Mast cells play no role in the pathogenesis of postoperative ileus induced by intestinal manipulation.

INTRODUCTION: Intestinal manipulation (IM) during abdominal surgery results in intestinal inflammation leading to hypomotility or ileus. Mast cell activation is thought to play a crucial role in the pathophysiology of postoperative ileus (POI). However, this conclusion was mainly drawn using mast ce...

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Main Authors: Pedro J Gomez-Pinilla, Giovanna Farro, Martina Di Giovangiulio, Nathalie Stakenborg, Andrea Némethova, Annick de Vries, Adrian Liston, Thorsten B Feyerabend, Hans-Reimer Rodewald, Guy E Boeckxstaens, Gianluca Matteoli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3887017?pdf=render