Mast cells play no role in the pathogenesis of postoperative ileus induced by intestinal manipulation.

Mast cells play no role in the pathogenesis of postoperative ileus induced by intestinal manipulation.

INTRODUCTION: Intestinal manipulation (IM) during abdominal surgery results in intestinal inflammation leading to hypomotility or ileus. Mast cell activation is thought to play a crucial role in the pathophysiology of postoperative ileus (POI). However, this conclusion was mainly drawn using mast ce...

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Main Authors: Pedro J Gomez-Pinilla, Giovanna Farro, Martina Di Giovangiulio, Nathalie Stakenborg, Andrea Némethova, Annick de Vries, Adrian Liston, Thorsten B Feyerabend, Hans-Reimer Rodewald, Guy E Boeckxstaens, Gianluca Matteoli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3887017?pdf=render

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