Inhibition of ITCH Suppresses Proliferation and Induces Apoptosis of Lung Cancer Cells

Background/Aims: The E3 ubiquitin ligase ITCH plays an important role in invasive and metastatic cancers. However, the role of ITCH in the progression of lung cancer has not been fully described. Methods: Real-time PCR was used to detect the expression of ITCH mRNA in the tumor tissues and paracarci...

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Bibliographic Details
Main Authors: Peng-Fei Li, Qi-Gang Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
EMT
Online Access:https://www.karger.com/Article/FullText/492295