Atomic Model and Micelle Dynamics of QS-21 Saponin

Atomic Model and Micelle Dynamics of QS-21 Saponin

QS-21 is a saponin extracted from Quillaja saponaria, widely investigated as a vaccine immunoadjuvant. However, QS-21 use is mainly limited by its chemical instability, significant variety in molecular composition and low tolerance dose in mammals. Also, this compound tends to form micelles in a con...

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Bibliographic Details
Main Authors: Conrado Pedebos, Laércio Pol-Fachin, Ramon Pons, Cilâine V. Teixeira, Hugo Verli
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Molecules
Subjects:
QS-21
saponins
glycoconjugates
molecular dynamics
SAXS
micelle
adjuvant
Online Access:http://www.mdpi.com/1420-3049/19/3/3744

Internet

http://www.mdpi.com/1420-3049/19/3/3744

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