Expression and function of variants of human catecholamine transporters lacking the fifth transmembrane region encoded by exon 6.

BACKGROUND: The transporters for dopamine (DAT) and norepinephrine (NET) are members of the Na+- and Cl--dependent neurotransmitter transporter family SLC6. There is a line of evidence that alternative splicing results in several isoforms of neurotransmitter transporters including NET. However, its...

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Main Authors: Chiharu Sogawa, Chieko Mitsuhata, Kei Kumagai-Morioka, Norio Sogawa, Kazumi Ohyama, Katsuya Morita, Katsuyuki Kozai, Toshihiro Dohi, Shigeo Kitayama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2916826?pdf=render