CXCR7 functions as a scavenger for CXCL12 and CXCL11.

CXCR7 functions as a scavenger for CXCL12 and CXCL11.

BACKGROUND:CXCR7 (RDC1), the recently discovered second receptor for CXCL12, is phylogenetically closely related to chemokine receptors, but fails to couple to G-proteins and to induce typical chemokine receptor mediated cellular responses. The function of CXCR7 is controversial. Some studies sugges...

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Bibliographic Details
Main Authors: Ulrike Naumann, Elisabetta Cameroni, Monika Pruenster, Harsha Mahabaleshwar, Erez Raz, Hans-Günter Zerwes, Antal Rot, Marcus Thelen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2820091?pdf=render

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http://europepmc.org/articles/PMC2820091?pdf=render

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