Multiple gene targeting siRNAs for down regulation of Immediate Early-2 (Ie2) and DNA polymerase genes mediated inhibition of novel rat Cytomegalovirus (strain All-03)

Multiple gene targeting siRNAs for down regulation of Immediate Early-2 (Ie2) and DNA polymerase genes mediated inhibition of novel rat Cytomegalovirus (strain All-03)

Abstract Background Cytomegalovirus (CMV) is an opportunistic pathogen that causes severe complications in congenitally infected newborns and non-immunocompetent individuals. Developing an effective vaccine is a major public health priority and current drugs are fronting resistance and side effects...

Full description

Bibliographic Details
Main Authors: Krishnan Nair Balakrishnan, Ashwaq Ahmed Abdullah, Jamilu Abubakar Bala, Faez Firdaus Abdullah Jesse, Che Azurahanim Che Abdullah, Mustapha Mohamed Noordin, Mohd Lila Mohd-Azmi
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Virology Journal
Subjects:
Cytomegalovirus
Combinations
Small interfering RNA
Replication
Gene expression
Online Access:http://link.springer.com/article/10.1186/s12985-020-01436-5

Internet

http://link.springer.com/article/10.1186/s12985-020-01436-5

Similar Items