Milk-derived tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) differentially modulate angiotensin II effects on vascular smooth muscle cells

Milk-derived tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) differentially modulate angiotensin II effects on vascular smooth muscle cells

Hyperactivity of the Renin-Angiotensin System (RAS) is a hallmark of hypertension. Angiotensin II (AngII), the active component of RAS, not only promotes vasoconstriction but also contributes to proliferation, inflammation and oxidative stress in vascular smooth muscle cells (VSMC) that predispose t...

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Bibliographic Details
Main Authors: Subhadeep Chakrabarti, Wang Liao, Sandra T. Davidge, Jianping Wu
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Journal of Functional Foods
Subjects:
IPP
VPP
Lactotripeptides
VSMC
Inflammation
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S175646461630411X

Internet

http://www.sciencedirect.com/science/article/pii/S175646461630411X

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