Co-administration of silymarin and deferoxamine against kidney, liver and heart iron deposition in male iron overload rat model

Co-administration of silymarin and deferoxamine against kidney, liver and heart iron deposition in male iron overload rat model

Background: Tissue iron deposition may disturb functions of the organs. In many diseases like thalassemia, the patients suffer from iron deposition in kidney and heart tissues. Deferoxamine (DF) is a synthetic iron chelator and silymarin (SM) is an antioxidant and also a candidate for iron chelating...

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Bibliographic Details
Main Authors: Mitra Navidi-Shishaone, Soheila Mohhebi, Mehdi Nematbakhsh, Shahla Roozbehani, Ardeshir Talebi, Zahra Pezeshki, Fatemeh Eshraghi-Jazi, Safoora Mazaheri, Sohiela Shirdavani, Marjan Gharagozloo, Behjat Alsaadat Moaeidi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:International Journal of Preventive Medicine
Subjects:
Deferoxamine
heart
iron deposition
kidney
liver
silymarin
Online Access:http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2014;volume=5;issue=1;spage=110;epage=116;aulast=Navidi-Shishaone

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http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2014;volume=5;issue=1;spage=110;epage=116;aulast=Navidi-Shishaone

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