Time-Programmed Delivery of Sorafenib and Anti-CD47 Antibody via a Double-Layer-Gel Matrix for Postsurgical Treatment of Breast Cancer

Time-Programmed Delivery of Sorafenib and Anti-CD47 Antibody via a Double-Layer-Gel Matrix for Postsurgical Treatment of Breast Cancer

Abstract The highly immunosuppressive microenvironment after surgery has a crucial impact on the recurrence and metastasis in breast cancer patients. Programmable delivery of immunotherapy-involving combinations through a single drug delivery system is highly promising, yet greatly challenging, to r...

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Bibliographic Details
Main Authors: Liping Huang, Yiyi Zhang, Yanan Li, Fanling Meng, Hongyu Li, Huimin Zhang, Jiasheng Tu, Chunmeng Sun, Liang Luo
Format: Article
Language:English
Published: SpringerOpen 2021-06-01
Series:Nano-Micro Letters
Subjects:
Hierarchical hydrogel
Sorafenib
Postoperative immunosuppression reversal
Tumor-associated macrophages
Anti-CD47 antibody
Online Access:https://doi.org/10.1007/s40820-021-00647-x

Internet

https://doi.org/10.1007/s40820-021-00647-x

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