Super-resolution imaging of synaptic and Extra-synaptic AMPA receptors with different-sized fluorescent probes

Super-resolution imaging of synaptic and Extra-synaptic AMPA receptors with different-sized fluorescent probes

Previous studies tracking AMPA receptor (AMPAR) diffusion at synapses observed a large mobile extrasynaptic AMPAR pool. Using super-resolution microscopy, we examined how fluorophore size and photostability affected AMPAR trafficking outside of, and within, post-synaptic densities (PSDs) from rats....

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Bibliographic Details
Main Authors: Sang Hak Lee, Chaoyi Jin, En Cai, Pinghua Ge, Yuji Ishitsuka, Kai Wen Teng, Andre A de Thomaz, Duncan Nall, Murat Baday, Okunola Jeyifous, Daniel Demonte, Christopher M Dundas, Sheldon Park, Jary Y Delgado, William N Green, Paul R Selvin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-07-01
Series:eLife
Subjects:
AMAP receptors
synapses
super-resolution imaging
small qdots
glutamate receptor
single molecule tracking
Online Access:https://elifesciences.org/articles/27744

Internet

https://elifesciences.org/articles/27744

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