Rapid target validation in a Cas9-inducible hiPSC derived kidney model

Rapid target validation in a Cas9-inducible hiPSC derived kidney model

Abstract Recent advances in induced pluripotent stem cells (iPSCs), genome editing technologies and 3D organoid model systems highlight opportunities to develop new in vitro human disease models to serve drug discovery programs. An ideal disease model would accurately recapitulate the relevant disea...

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Bibliographic Details
Main Authors: Yasaman Shamshirgaran, Anna Jonebring, Anna Svensson, Isabelle Leefa, Mohammad Bohlooly-Y, Mike Firth, Kevin J. Woollard, Alexis Hofherr, Ian M. Rogers, Ryan Hicks
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95986-5

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https://doi.org/10.1038/s41598-021-95986-5

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