Frequency of SCA8, SCA10, SCA12, SCA36, FXTAS and C9orf72 repeat expansions in SCA patients negative for the most common SCA subtypes

Frequency of SCA8, SCA10, SCA12, SCA36, FXTAS and C9orf72 repeat expansions in SCA patients negative for the most common SCA subtypes

Abstract Background Spinocerebellar ataxia (SCA) subtypes are often caused by expansions in non-coding regions of genes like SCA8, SCA10, SCA12 and SCA36. Other ataxias are known to be associated with repeat expansions such as fragile X-associated tremor ataxia syndrome (FXTAS) or expansions in the...

Full description

Bibliographic Details
Main Authors: Gülsah Aydin, Gabriele Dekomien, Sabine Hoffjan, Wanda Maria Gerding, Jörg T. Epplen, Larissa Arning
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Neurology
Subjects:
Spinocerebellar ataxia
Repeat expansions
SCA8
Fxtas
C9orf72
Online Access:http://link.springer.com/article/10.1186/s12883-017-1009-9

Internet

http://link.springer.com/article/10.1186/s12883-017-1009-9

Similar Items