New and distinct chronic wasting disease strains associated with cervid polymorphism at codon 116 of the Prnp gene.

New and distinct chronic wasting disease strains associated with cervid polymorphism at codon 116 of the Prnp gene.

Chronic wasting disease (CWD) is a prion disease affecting cervids. Polymorphisms in the prion protein gene can result in extended survival of CWD-infected animals. However, the impact of polymorphisms on cellular prion protein (PrPC) and prion properties is less understood. Previously, we character...

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Bibliographic Details
Main Authors: Samia Hannaoui, Elizabeth Triscott, Camilo Duque Velásquez, Sheng Chun Chang, Maria Immaculata Arifin, Irina Zemlyankina, Xinli Tang, Trent Bollinger, Holger Wille, Debbie McKenzie, Sabine Gilch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009795

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https://doi.org/10.1371/journal.ppat.1009795

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