Resistance to inhibitors of the human immunodeficiency virus type 1 integration
This review will summarize the role of integrase in HIV-1 infection, the mechanism of integrase inhibitors and resistance with an emphasis on raltegravir (RAL), the first integrase inhibitor licensed to treat HIV-1 infection. Keywords: antiretrovirals, integrase inhibitors, raltegravir
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| Format: | Article |
| Language: | English |
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Elsevier
2010-09-01
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| Series: | Brazilian Journal of Infectious Diseases |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1413867010701033 |