Erlotinib inhibits growth of a patient-derived chordoma xenograft.

Chordomas are rare primary bone tumors that occur along the neuraxis. Primary treatment is surgery, often followed by radiotherapy. Treatment options for patients with recurrence are limited and, notably, there are no FDA approved therapeutic agents. Development of therapeutic options has been limit...

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Bibliographic Details
Main Authors: I-Mei Siu, Jacob Ruzevick, Qi Zhao, Nick Connis, Yuchen Jiao, Chetan Bettegowda, Xuewei Xia, Peter C Burger, Christine L Hann, Gary L Gallia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3829812?pdf=render