Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping

Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping

High-throughput sequencing and analyzes of antibody repertoire provide important information on immune responses, but current methodologies are limited in sequence assembly precision and haplotype inference validity. Here the authors propose a new Bayesian haplotyping method, and attest its broad ap...

Full description

Bibliographic Details
Main Authors: Moriah Gidoni, Omri Snir, Ayelet Peres, Pazit Polak, Ida Lindeman, Ivana Mikocziova, Vikas Kumar Sarna, Knut E. A. Lundin, Christopher Clouser, Francois Vigneault, Andrew M. Collins, Ludvig M. Sollid, Gur Yaari
Format: Article
Language:English
Published: Nature Publishing Group 2019-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08489-3

Internet

https://doi.org/10.1038/s41467-019-08489-3

Similar Items