Anticancer Activities of the Quinone-Methide Triterpenes Maytenin and 22-β-hydroxymaytenin Obtained from Cultivated <i>Maytenus ilicifolia</i> Roots Associated with Down-Regulation of miRNA-27a and miR-20a/miR-17-5p

Anticancer Activities of the Quinone-Methide Triterpenes Maytenin and 22-β-hydroxymaytenin Obtained from Cultivated <i>Maytenus ilicifolia</i> Roots Associated with Down-Regulation of miRNA-27a and miR-20a/miR-17-5p

Natural triterpenes exhibit a wide range of biological activities. Since this group of secondary metabolites is structurally diverse, effects may vary due to distinct biochemical interactions within biological systems. In this work, we investigated the anticancer-related activities of the quinone-me...

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Bibliographic Details
Main Authors: Camila Hernandes, Lucyene Miguita, Romario Oliveira de Sales, Elisangela de Paula Silva, Pedro Omori Ribeiro de Mendonça, Bruna Lorencini da Silva, Maria de Fatima Guarizo Klingbeil, Monica Beatriz Mathor, Erika Bevilaqua Rangel, Luciana Cavalheiro Marti, Juliana da Silva Coppede, Fabio Daumas Nunes, Ana Maria Soares Pereira, Patricia Severino
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
triterpene
squamous cell carcinoma
quinone-methide
microrna
Online Access:https://www.mdpi.com/1420-3049/25/3/760

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https://www.mdpi.com/1420-3049/25/3/760

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