Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity

Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity

Hepatokines are proteins secreted by the liver that can regulate whole body metabolism. Here the authors identify apolipoprotein J as a hepatokine that regulates muscle glucose metabolism and insulin resistance through a low-density lipoprotein receptor-related protein−2 mediated mechanism in mice....

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Bibliographic Details
Main Authors: Ji A Seo, Min-Cheol Kang, Won-Mo Yang, Won Min Hwang, Sang Soo Kim, Soo Hyun Hong, Jee-In Heo, Achana Vijyakumar, Leandro Pereira de Moura, Aykut Uner, Hu Huang, Seung Hwan Lee, Inês S. Lima, Kyong Soo Park, Min Seon Kim, Yossi Dagon, Thomas E. Willnow, Vanita Aroda, Theodore P. Ciaraldi, Robert R. Henry, Young-Bum Kim
Format: Article
Language:English
Published: Nature Publishing Group 2020-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15963-w

Internet

https://doi.org/10.1038/s41467-020-15963-w

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