Manipulating the In Vivo Behaviour of <sup>68</sup>Ga with Tris(Hydroxypyridinone) Chelators: Pretargeting and Blood Clearance

Pretargeting is widely explored in immunoPET as a strategy to reduce radiation exposure of non-target organs and allow the use of short-lived radionuclides that would not otherwise be compatible with the slow pharmacokinetic profiles of antibodies. Here we investigate a pretargeting strategy based o...

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Bibliographic Details
Main Authors: Cinzia Imberti, Pierre Adumeau, Julia E. Blower, Fahad Al Salemee, Julia Baguña Torres, Jason S. Lewis, Brian M. Zeglis, Samantha Y. A. Terry, Philip J. Blower
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/4/1496