Genome and Functional Characterization of Colonization Factor Antigen I- and CS6-Encoding Heat-Stable Enterotoxin-Only Enterotoxigenic Escherichia coli Reveals Lineage and Geographic Variation

Genome and Functional Characterization of Colonization Factor Antigen I- and CS6-Encoding Heat-Stable Enterotoxin-Only Enterotoxigenic Escherichia coli Reveals Lineage and Geographic Variation

Comparative genomics and functional characterization were used to analyze a global collection of CFA/I and CS6 ST-only ETEC isolates associated with human diarrhea, demonstrating differences in the genomic content of CFA/I and CS6 isolates related to CF type, lineage, and geographic location of isol...

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Bibliographic Details
Main Authors: Tracy H. Hazen, Sushma Nagaraj, Sunil Sen, Jasnehta Permala-Booth, Felipe Del Canto, Roberto Vidal, Eileen M. Barry, Jacob P. Bitoun, Wilbur H. Chen, Sharon M. Tennant, David A. Rasko
Format: Article
Language:English
Published: American Society for Microbiology 2019-01-01
Series:mSystems
Subjects:
Escherichia coli
comparative genomics
heat-stable toxin
Online Access:https://doi.org/10.1128/mSystems.00329-18

Internet

https://doi.org/10.1128/mSystems.00329-18

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