Safety of oral administration of high doses of ivermectin by means of biocompatible polyelectrolytes formulation

Safety of oral administration of high doses of ivermectin by means of biocompatible polyelectrolytes formulation

The FDA-approved drug ivermectin is applied for treatments of onchocerciasis and lymphatic filariasis. The anti-cancer and anti-viral activities have been demonstrated stressing possibilities for the drug repurposing and therefore new information on high dosage safety is on demand. We analyzed in vi...

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Bibliographic Details
Main Authors: Rafael R.M. Madrid, Patrick D. Mathews, Ana C.M.F. Patta, Anai P. Gonzales-Flores, Carlos A.B. Ramirez, Vera L.S. Rigoni, Marcos Tavares-Dias, Omar Mertins
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Heliyon
Subjects:
High dosage
Drug repurposing
Animal model
Histochemistry
Formulation
Immunofluorescence
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020326633

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http://www.sciencedirect.com/science/article/pii/S2405844020326633

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