Multimodality imaging methods for assessing retinoblastoma orthotopic xenograft growth and development.

Genomic studies of the pediatric ocular tumor retinoblastoma are paving the way for development of targeted therapies. Robust model systems such as orthotopic xenografts are necessary for testing such therapeutics. One system involves bioluminescence imaging of luciferase-expressing human retinoblas...

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Bibliographic Details
Main Authors: Timothy W Corson, Brian C Samuels, Andrea A Wenzel, Anna J Geary, Amanda A Riley, Brian P McCarthy, Helmut Hanenberg, Barbara J Bailey, Pamela I Rogers, Karen E Pollok, Gangaraju Rajashekhar, Paul R Territo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24901248/?tool=EBI