NR4A1 promotes PDGF-BB-induced cell colony formation in soft agar.

The fibroblast mitogen platelet-derived growth factor -BB (PDGF-BB) induces a transient expression of the orphan nuclear receptor NR4A1 (also named Nur77, TR3 or NGFIB). The aim of the present study was to investigate the pathways through which NR4A1 is induced by PDGF-BB and its functional role. We...

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Bibliographic Details
Main Authors: Glenda Eger, Natalia Papadopoulos, Johan Lennartsson, Carl-Henrik Heldin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182636?pdf=render