Global Overexpression of ET-1 Decreases Blood Pressure - A Systematic Review and Meta-Analysis of ET-1 Transgenic Mice

Background/Aims: ET-1 has independent effects on blood pressure regulation in vivo, it is involved in tubular water and salt excretion, promotes constriction of smooth muscle cells, modulates sympathetic nerve activity, and activates the liberation of nitric oxide. To determine the net effect of the...

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Bibliographic Details
Main Authors: Yong Ping Lu, Oleg Tsuprykov, Nicolas Vignon-Zellweger, Susi Heiden, Berthold Hocher
Format: Article
Language:English
Published: Karger Publishers 2016-11-01
Series:Kidney & Blood Pressure Research
Subjects:
Online Access:http://www.karger.com/Article/FullText/450567