The effects of exercise on hypothalamic neurodegeneration of Alzheimer's disease mouse model.

Alzheimer's disease is a neurodegenerative disorder that affects the central nervous system. In this study, we characterized and examined the early metabolic changes in the triple transgenic mouse AD model (3xtg-AD), and their relationship with the hypothalamus, a key regulator of metabolism in...

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Bibliographic Details
Main Authors: Khoa Do, Brenton Thomas Laing, Taylor Landry, Wyatt Bunner, Naderi Mersaud, Tomoko Matsubara, Peixin Li, Yuan Yuan, Qun Lu, Hu Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5749759?pdf=render