Exploring genetic alterations in circulating tumor DNA from cerebrospinal fluid of pediatric medulloblastoma

Abstract Medulloblastoma (MB) is the most common type of brain malignancy in children. Molecular profiling has become an important component to select patients for therapeutic approaches, allowing for personalized therapy. In this study, we successfully identified detectable levels of tumor-derived...

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Bibliographic Details
Main Authors: Yanling Sun, Miao Li, Siqi Ren, Yan Liu, Jin Zhang, Shuting Li, Wenchao Gao, Xiaojun Gong, Jingjing Liu, Yuan Wang, Shuxu Du, Liming Sun, Wanshui Wu, Yongji Tian
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85178-6