Primary Human Fibroblasts in Culture Switch to a Myofibroblast-Like Phenotype Independently of TGF Beta

Primary Human Fibroblasts in Culture Switch to a Myofibroblast-Like Phenotype Independently of TGF Beta

Fibroblasts are the prevalent cell type and main source for extracellular matrix (ECM) in connective tissue. Depending on their origin, fibroblasts play a central role in non-pathological tissue remodeling and disease like fibrosis. This study examined the effect of established culture conditions of...

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Bibliographic Details
Main Authors: Ulrike Baranyi, Birgitta Winter, Alfred Gugerell, Balazs Hegedus, Christine Brostjan, Günther Laufer, Barbara Messner
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cells
Subjects:
fibroblast
myofibroblast phenotype
alpha smooth muscle actin
CD90
ascorbic acid
procollagen I
Online Access:https://www.mdpi.com/2073-4409/8/7/721

Internet

https://www.mdpi.com/2073-4409/8/7/721

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