Phenotypic Characterization by Mass Cytometry of the Microenvironment in Ovarian Cancer and Impact of Tumor Dissociation Methods

Phenotypic Characterization by Mass Cytometry of the Microenvironment in Ovarian Cancer and Impact of Tumor Dissociation Methods

Improved molecular dissection of the tumor microenvironment (TME) holds promise for treating high-grade serous ovarian cancer (HGSOC), a gynecological malignancy with high mortality. Reliable disease-related biomarkers are scarce, but single-cell mapping of the TME could identify patient-specific pr...

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Bibliographic Details
Main Authors: Shamundeeswari Anandan, Liv Cecilie V. Thomsen, Stein-Erik Gullaksen, Tamim Abdelaal, Katrin Kleinmanns, Jørn Skavland, Geir Bredholt, Bjørn Tore Gjertsen, Emmet McCormack, Line Bjørge
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
high-grade serous ovarian cancer (HGSOC)
single-cell mass cytometry
Cytometry by Time-of-Flight (CyTOF)
tumor microenvironment (TME)
cell expression profile
tumor dissociation
Online Access:https://www.mdpi.com/2072-6694/13/4/755

Internet

https://www.mdpi.com/2072-6694/13/4/755

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