MITF - A controls branching morphogenesis and nephron endowment.
Congenital nephron number varies widely in the human population and individuals with low nephron number are at risk of developing hypertension and chronic kidney disease. The development of the kidney occurs via an orchestrated morphogenetic process where metanephric mesenchyme and ureteric bud reci...
Main Authors: | , , , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-12-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC5746285?pdf=render |