Effects of Silica and Titanium Oxide Particles on a Human Neural Stem Cell Line: Morphology, Mitochondrial Activity, and Gene Expression of Differentiation Markers

Effects of Silica and Titanium Oxide Particles on a Human Neural Stem Cell Line: Morphology, Mitochondrial Activity, and Gene Expression of Differentiation Markers

Several in vivo studies suggest that nanoparticles (smaller than 100 nm) have the ability to reach the brain tissue. Moreover, some nanoparticles can penetrate into the brains of murine fetuses through the placenta by intravenous administration to pregnant mice. However, it is not clear whether the...

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Bibliographic Details
Main Authors: Kouki Fujioka, Sanshiro Hanada, Yuriko Inoue, Keisuke Sato, Kenji Hirakuri, Kouichi Shiraishi, Fumihide Kanaya, Keiichi Ikeda, Ritsuko Usui, Kenji Yamamoto, Seung U. Kim, Yoshinobu Manome
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:International Journal of Molecular Sciences
Subjects:
silica
titanium oxide
nano
toxicity
neural stem cell
neural progenitor cell
differentiation
Online Access:http://www.mdpi.com/1422-0067/15/7/11742

Internet

http://www.mdpi.com/1422-0067/15/7/11742

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