Differences in IgG Fc Glycosylation Are Associated with Outcome of Pediatric Meningococcal Sepsis

Differences in IgG Fc Glycosylation Are Associated with Outcome of Pediatric Meningococcal Sepsis

Pediatric meningococcal sepsis often results in morbidity and/or death, especially in young children. Our understanding of the reasons why young children are more susceptible to both the meningococcal infection itself and a more fulminant course of the disease is limited. Immunoglobulin G (IgG) is i...

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Bibliographic Details
Main Authors: Noortje de Haan, Navin P. Boeddha, Ebru Ekinci, Karli R. Reiding, Marieke Emonts, Jan A. Hazelzet, Manfred Wuhrer, Gertjan J. Driessen
Format: Article
Language:English
Published: American Society for Microbiology 2018-06-01
Series:mBio
Subjects:
children
critical care
Fc glycosylation
immunoglobulin G
meningococcal sepsis
N-glycan
outcome
Online Access:https://doi.org/10.1128/mBio.00546-18

Internet

https://doi.org/10.1128/mBio.00546-18

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