Advancing chimeric antigen receptor T cell therapy with CRISPR/Cas9

Advancing chimeric antigen receptor T cell therapy with CRISPR/Cas9

ABSTRACT The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated 9 (CRISPR/Cas9) system, an RNA-guided DNA targeting technology, is triggering a revolution in the field of biology. CRISPR/Cas9 has demonstrated great potential for genetic manipulation. In this review,...

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Bibliographic Details
Main Authors: Jiangtao Ren, Yangbing Zhao
Format: Article
Language:English
Published: SpringerOpen 2017-04-01
Series:Protein & Cell
Subjects:
CRISPR/Cas9
chimeric antigen receptor
T lymphocytes
adoptive immunotherapy
gene therapy
Online Access:http://link.springer.com/article/10.1007/s13238-017-0410-x

Internet

http://link.springer.com/article/10.1007/s13238-017-0410-x

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