Derivation of trophoblast stem cells from naïve human pluripotent stem cells

Derivation of trophoblast stem cells from naïve human pluripotent stem cells

Naïve human pluripotent stem cells (hPSCs) provide a unique experimental platform of cell fate decisions during pre-implantation development, but their lineage potential remains incompletely characterized. As naïve hPSCs share transcriptional and epigenomic signatures with trophoblast cells, it has...

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Bibliographic Details
Main Authors: Chen Dong, Mariana Beltcheva, Paul Gontarz, Bo Zhang, Pooja Popli, Laura A Fischer, Shafqat A Khan, Kyoung-mi Park, Eun-Ja Yoon, Xiaoyun Xing, Ramakrishna Kommagani, Ting Wang, Lilianna Solnica-Krezel, Thorold W Theunissen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-02-01
Series:eLife
Subjects:
naive pluripotency
primed pluripotency
trophectoderm
trophoblast stem cells
RNA-seq
ATAC-seq
Online Access:https://elifesciences.org/articles/52504

Internet

https://elifesciences.org/articles/52504

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