Glycine increases glyoxalase‐1 function by promoting nuclear factor erythroid 2‐related factor 2 translocation into the nucleus of kidney cells of streptozotocin‐induced diabetic rats

Abstract Aims/Introduction We have previously reported that glycine suppresses the advanced glycation end‐products signaling pathway and mitigates subsequent oxidative stress in the kidneys of diabetic rats. In the present study, we investigated whether this beneficial effect was associated with upr...

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Bibliographic Details
Main Authors: Ziwei Wang, Dan Zhao, Lei Chen, Jingjing Li, Geheng Yuan, Guosheng Yang, Hong Zhang, Xiaohui Guo, Junqing Zhang
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Journal of Diabetes Investigation
Subjects:
Online Access:https://doi.org/10.1111/jdi.13032