The Loss of α- and β-Tubulin Proteins Are a Pathological Hallmark of Chronic Alcohol Consumption and Natural Brain Ageing

The Loss of α- and β-Tubulin Proteins Are a Pathological Hallmark of Chronic Alcohol Consumption and Natural Brain Ageing

Repetitive excessive alcohol intoxication leads to neuronal damage and brain shrinkage. We examined cytoskeletal protein expression in human post-mortem tissue from Brodmann’s area 9 of the prefrontal cortex (PFC). Brain samples from 44 individuals were divided into equal groups of 11 cont...

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Bibliographic Details
Main Authors: Wajana L. Labisso, Ana-Caroline Raulin, Lucky L. Nwidu, Artur Kocon, Declan Wayne, Amaia M. Erdozain, Benito Morentin, Daniela Schwendener, George Allen, Jack Enticott, Henry K. Gerdes, Laura Johnson, John Grzeskowiak, Fryni Drizou, Rebecca Tarbox, Natalia A. Osna, Kusum K. Kharbanda, Luis F. Callado, Wayne G. Carter
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Brain Sciences
Subjects:
acetylation
ageing
alcoholism
alcohol-related brain damage
α-tubulin
β-tubulin
HDAC6
MAP-2
MAP-tau
pre-frontal cortex
Online Access:http://www.mdpi.com/2076-3425/8/9/175

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http://www.mdpi.com/2076-3425/8/9/175

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