Testing non-inferiority of blended versus face-to-face cognitive behavioural therapy for severe fatigue in patients with multiple sclerosis and the effectiveness of blended booster sessions aimed at improving long-term outcome following both therapies: study protocol for two observer-blinded randomized clinical trials

Abstract Background Cognitive behavioural therapy (CBT) has been found to be effective in reducing fatigue severity in MS patients directly following treatment. However, long-term effects are inconsistent leaving room for improvement. In addition, individual face-to-face CBT draws heavily on limited...

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Bibliographic Details
Main Authors: Marieke Houniet-de Gier, Heleen Beckerman, Kimberley van Vliet, Hans Knoop, Vincent de Groot
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-019-3825-2