Development and Evaluation of a Novel Mucoadhesive Film Containing Acmella oleracea Extract for Oral Mucosa Topical Anesthesia.

PURPOSE:To develop an anesthetic mucoadhesive film containing Acmella oleracea (jambu) extract for topical use on oral mucosa. METHODS:Ethanolic extracts from aerial parts of jambu were prepared by maceration. Pigment removal was obtained by adsorption with activated carbon. Three mucoadhesive films...

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Main Authors: Verônica Santana de Freitas-Blanco, Michelle Franz-Montan, Francisco Carlos Groppo, João Ernesto de Carvalho, Glyn Mara Figueira, Luciano Serpe, Ilza Maria Oliveira Sousa, Viviane Aparecida Guilherme Damasio, Lais Thiemi Yamane, Eneida de Paula, Rodney Alexandre Ferreira Rodrigues
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5023158?pdf=render