Purinergic signaling mediates oxidative stress in UVA-exposed THP-1 cells

Purinergic signaling mediates oxidative stress in UVA-exposed THP-1 cells

Ultraviolet A (UVA) radiation, the major UV component of solar radiation, can penetrate easily to the dermis, where it causes significant damage to cellular components by inducing formation of reactive oxygen species (ROS). On the other hand, extracellular ATP is released in response to various stim...

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Bibliographic Details
Main Authors: Ayumi Kawano, Akimitsu Hayakawa, Shuji Kojima, Mitsutoshi Tsukimoto, Hikaru Sakamoto
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Toxicology Reports
Subjects:
Ultraviolet A
ATP
P2X7 receptor
Reactive oxygen species
Cell death
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750015000177

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http://www.sciencedirect.com/science/article/pii/S2214750015000177

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