Globular Adiponectin Inhibits the Apoptosis of Mesenchymal Stem Cells Induced by Hypoxia and Serum Deprivation via the AdipoR1-Mediated Pathway

Globular Adiponectin Inhibits the Apoptosis of Mesenchymal Stem Cells Induced by Hypoxia and Serum Deprivation via the AdipoR1-Mediated Pathway

Background/Aims: Poor viability of transplanted mesenchymal stem cells (MSCs) within the ischemic heart limits their therapeutic potential for cardiac repair. Globular adiponectin (gAPN) exerts anti-apoptotic effects on several types of stem cells. Herein, we investigated the effect of gAPN on the M...

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Bibliographic Details
Main Authors: Xia-Qiu Tian, Yue-Jin Yang, Qing Li, Pei-Sen Huang, Xiang-Dong Li, Chen Jin, Kang Qi, Lei-Pei Jiang, Gui-Hao Chen
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Mesenchymal stem cells
Apoptosis
Hypoxia and serum deprivation
AMPK
Signaling pathway
Adiponectin
Online Access:http://www.karger.com/Article/FullText/443044

Internet

http://www.karger.com/Article/FullText/443044

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