Targeted RNA-Seq Reveals the <i>M. tuberculosis</i> Transcriptome from an In Vivo Infection Model

Targeted RNA-Seq Reveals the <i>M. tuberculosis</i> Transcriptome from an In Vivo Infection Model

The study of host-pathogen interactions using in vivo models with intracellular pathogens like Mycobacterium tuberculosis (Mtb) entails technical limitations, such as: (i) Selecting an efficient differential lysis system to enrich the pathogen cells; (ii) obtaining sufficient high-quality RNA; and (...

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Bibliographic Details
Main Authors: Fernanda Cornejo-Granados, Gamaliel López-Leal, Dulce A. Mata-Espinosa, Jorge Barrios-Payán, Brenda Marquina-Castillo, Edgar Equihua-Medina, Zyanya L. Zatarain-Barrón, Camilo Molina-Romero, Rogelio Hernández-Pando, Adrian Ochoa-Leyva
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biology
Subjects:
transcriptome
tuberculosis
host-pathogen
RNA-seq
in vivo infection
Online Access:https://www.mdpi.com/2079-7737/10/9/848

Internet

https://www.mdpi.com/2079-7737/10/9/848

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