URG4 mediates cell proliferation and cell cycle in osteosarcoma via GSK3β/β-catenin/cyclin D1 signaling pathway

URG4 mediates cell proliferation and cell cycle in osteosarcoma via GSK3β/β-catenin/cyclin D1 signaling pathway

Abstract Background Osteosarcoma is one of the most common malignant bone tumors with the annual global incidence of approximately four per million. Upregulated gene 4 (URG4) expression in the osteosarcoma tissue is closely associated with recurrence, metastasis, and poor prognosis of osteosarcoma....

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Bibliographic Details
Main Authors: Yayun Liu, Yizhe Xi, Gang Chen, Xidong Wu, Maolin He
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Upregulated gene 4
Osteosarcoma
GSK3β/β-catenin/cyclin D1
Cell proliferation
Cell cycle
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s13018-020-01681-y

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http://link.springer.com/article/10.1186/s13018-020-01681-y

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