Differential effects of rapamycin and dexamethasone in mouse models of established allergic asthma.

The mammalian target of rapamycin (mTOR) plays an important role in cell growth/differentiation, integrating environmental cues, and regulating immune responses. Our lab previously demonstrated that inhibition of mTOR with rapamycin prevented house dust mite (HDM)-induced allergic asthma in mice. He...

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Bibliographic Details
Main Authors: Elizabeth M Mushaben, Eric B Brandt, Gurjit K Khurana Hershey, Timothy D Le Cras
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3547928?pdf=render