Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25

Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25

Pfs25 is a transmission-blocking vaccine candidate for Plasmodium. Here, McLeod et al. analyze the antibody response to Pfs25 in sera from a clinical trial evaluating a Pfs25 vaccine candidate, identify a potent transmission-blocking antibody and determine recognized epitopes on Pfs25.

Bibliographic Details
Main Authors: Brandon McLeod, Kazutoyo Miura, Stephen W. Scally, Alexandre Bosch, Ngan Nguyen, Hanjun Shin, Dongkyoon Kim, Wayne Volkmuth, Sebastian Rämisch, Jessica A. Chichester, Stephen Streatfield, Colleen Woods, William R. Schief, Daniel Emerling, C. Richter King, Jean-Philippe Julien
Format: Article
Language:English
Published: Nature Publishing Group 2019-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11980-6

Internet

https://doi.org/10.1038/s41467-019-11980-6

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