TRPV1 Contributes to Cerebral Malaria Severity and Mortality by Regulating Brain Inflammation

Transient receptor potential vanilloid 1 (TRPV1) is a Ca+2-permeable channel expressed on neuronal and nonneuronal cells, known as an oxidative stress sensor. It plays a protective role in bacterial infection, and recent findings indicate that this receptor modulates monocyte populations in mice wit...

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Bibliographic Details
Main Authors: Domingos Magno Santos Pereira, Simone Aparecida Teixeira, Oscar Murillo, Erika Paula Machado Peixoto, Mizael Calácio Araújo, Nágila Caroline Fialho Sousa, Valério Monteiro-Neto, João Batista Calixto, Thiago Mattar Cunha, Cláudio Romero Farias Marinho, Marcelo Nicolás Muscará, Elizabeth Soares Fernandes
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/9451671