The Effect and Optimal Dosage of Dexmedetomidine Plus Sufentanil for Postoperative Analgesia in Elderly Patients With Postoperative Delirium and Early Postoperative Cognitive Dysfunction: A Single-Center, Prospective, Randomized, Double-Blind, Controlled Trial

The Effect and Optimal Dosage of Dexmedetomidine Plus Sufentanil for Postoperative Analgesia in Elderly Patients With Postoperative Delirium and Early Postoperative Cognitive Dysfunction: A Single-Center, Prospective, Randomized, Double-Blind, Controlled Trial

BackgroundPostoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are common complications after major surgery among elderly patients. Dexmedetomidine (DEX) is less frequently explored for its effects in patients with postoperative neurocognitive disorders. This study investigate...

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Bibliographic Details
Main Authors: Wenshuai Zhao, Yanan Hu, Hui Chen, Xifan Wang, Liping Wang, Yu Wang, Xiaohong Wu, Fei Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Neuroscience
Subjects:
dexmedetomidine
patient-controlled analgesia
postoperative delirium
postoperative cognitive dysfunction
elderly patients
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2020.549516/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2020.549516/full

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