The Role of Conformational Dynamics in Abacavir-Induced Hypersensitivity Syndrome
Abstract Abacavir is an antiretroviral drug used to reduce human immunodeficiency virus (HIV) replication and decrease the risk of developing acquired immune deficiency syndrome (AIDS). However, its therapeutic value is diminished by the fact that it is associated with drug hypersensitivity reaction...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-019-47001-1 |