SMARCAD1 Phosphorylation and Ubiquitination Are Required for Resection during DNA Double-Strand Break Repair

SMARCAD1 Phosphorylation and Ubiquitination Are Required for Resection during DNA Double-Strand Break Repair

Summary: The chromatin remodeling factor SMARCAD1, an SWI/SNF ATPase family member, has a role in 5′ end resection at DNA double-strand breaks (DSBs) to produce single-strand DNA (ssDNA), a critical step for subsequent checkpoint and repair factor loading to remove DNA damage. However, the mechanist...

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Bibliographic Details
Main Authors: Sharmistha Chakraborty, Raj K. Pandita, Shashank Hambarde, Abid R. Mattoo, Vijaya Charaka, Kazi M. Ahmed, Swaminathan P. Iyer, Clayton R. Hunt, Tej K. Pandita
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218300257

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http://www.sciencedirect.com/science/article/pii/S2589004218300257

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