Protective Role of rAAV-NDI1, Serotype 5, in an Acute MPTP Mouse Parkinson's Model

Defects in mitochondrial proton-translocating NADH-quinone oxidoreductase (complex I) have been implicated in a number of acquired and hereditary diseases including Leigh's syndrome and more recently Parkinson's disease. A limited number of strategies have been attempted to repair the dam...

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Bibliographic Details
Main Authors: Jennifer Barber-Singh, Byoung Boo Seo, Akemi Matsuno-Yagi, Takao Yagi
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.4061/2011/438370