Runs of homozygosity associated with speech delay in autism in a taiwanese han population: evidence for the recessive model.

Runs of homozygosity associated with speech delay in autism in a taiwanese han population: evidence for the recessive model.

Runs of homozygosity (ROH) may play a role in complex diseases. In the current study, we aimed to test if ROHs are linked to the risk of autism and related language impairment. We analyzed 546,080 SNPs in 315 Han Chinese affected with autism and 1,115 controls. ROH was defined as an extended homozyg...

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Bibliographic Details
Main Authors: Ping-I Lin, Po-Hsiu Kuo, Chia-Hsiang Chen, Jer-Yuarn Wu, Susan S-F Gau, Yu-Yu Wu, Shih-Kai Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3745408?pdf=render

Internet

http://europepmc.org/articles/PMC3745408?pdf=render

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